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Alpha Globin Known Family Variant Test

Virginia rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $398 · 10th–90th $316$1,6600%20%10th90th$398Professionalmedian $282 · 10th–90th $151$5620%10%10th90th$282$10.0$50.0$200.0$1.0K$5.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$794.33
Typical High
$1,479.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$316.23
Typical High
$707.95
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$371.54
Typical High
$1,513.56
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$151.36
Typical High
$251.19
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$323.59
Typical High
$363.08
Cigna
Setting
Facility
Modifier
Global
Typical Low
$380.19
Median
$933.25
Typical High
$1,905.46
Cigna
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$229.09
Typical High
$575.44
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$371.54
Median
$416.87
Typical High
$524.81
Medcost
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$416.87
Typical High
$630.96
Medcost
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$245.47
Typical High
$794.33
Sentara
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$446.68
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$446.68
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$371.54
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$190.55
Typical High
$436.52