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Alpha Globin Known Family Variant Test

South Carolina rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $692 · 10th–90th $263$1,7780%10%10th90th$692Professionalmedian $295 · 10th–90th $224$3980%50%10th90th$295$10.0$50.0$200.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$933.25
Typical High
$1,778.28
Aetna
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$295.12
Typical High
$338.84
BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$2,454.71
BCBS
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$371.54
Typical High
$549.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$707.95
Median
$1,230.27
Typical High
$2,137.96
Cigna
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$177.83
Typical High
$489.78
Medcost
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$338.84
Typical High
$501.19
United
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$371.54
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$223.87
Typical High
$371.54