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Alpha Globin Known Family Variant Test

Nebraska rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $525 · 10th–90th $224$1,0000%10%10th90th$525Professionalmedian $245 · 10th–90th $224$2,4550%50%10th90th$245$200.0$500.0$1.0K$2.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$1,000.00
Typical High
$1,862.09
Aetna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$245.47
Typical High
$2,454.71
BCBS
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$575.44
Typical High
$1,122.02
BCBS
Setting
Professional
Modifier
Global
Typical Low
$537.03
Median
$588.84
Typical High
$616.60
Cigna
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$724.44
Typical High
$891.25
Medica
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$562.34
Typical High
$1,778.28
Medica
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$223.87
Typical High
$1,096.48
Midlands
Setting
Professional
Modifier
Global
Typical Low
$776.25
Median
$776.25
Typical High
$776.25
United
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$354.81
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$223.87
Typical High
$1,047.13