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Alpha Globin Known Family Variant Test

North Carolina rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $331 · 10th–90th $282$1,2590%20%10th90th$331Professionalmedian $302 · 10th–90th $174$5370%20%10th90th$302$10.0$50.0$200.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$331.13
Typical High
$1,258.93
Aetna
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$302.00
Typical High
$489.78
BCBS
Setting
Facility
Modifier
Global
Typical Low
$630.96
Median
$851.14
Typical High
$933.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$338.84
Typical High
$602.56
Cigna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$812.83
Typical High
$1,698.24
Cigna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$181.97
Typical High
$524.81
Medcost
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$338.84
Typical High
$562.34
Medcost
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$245.47
Typical High
$245.47
United
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$446.68
Typical High
$457.09
United
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$223.87
Typical High
$398.11
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$1,778.28
Median
$1,778.28
Typical High
$1,778.28
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$1,862.09
Median
$1,862.09
Typical High
$2,818.38