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Alpha Globin Known Family Variant Test

Mississippi rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $468 · 10th–90th $339$6760%20%10th90th$468Professionalmedian $398 · 10th–90th $224$7590%10%20%10th90th$398$200.0$500.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$676.08
Typical High
$758.58
Aetna
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$436.52
Typical High
$758.58
BCBS
Setting
Facility
Modifier
Global
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
BCBS
Setting
Professional
Modifier
Global
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
Cigna
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$257.04
Typical High
$316.23
Cigna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$288.40
Typical High
$630.96
United
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$338.84
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$223.87
Typical High
$630.96