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Alpha Globin Known Family Variant Test

Mississippi rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated October 2026.

How much does Alpha Globin Known Family Variant Test cost?

$468

Typical negotiated rate. In Mississippi, October 2026.

Insurers have agreed to pay about $468 for this service. The price depends on where it is billed: about $417 from a physician practice, and about $468 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$417$204 to $562
FacilityA hospital or hospital-owned outpatient department$468$468 to $468

How much rates vary

Facilitymedian $468 · 10th to 90th $339 to $676Professionalmedian $417 · 10th to 90th $170 to $676
$200$500$1Kfacility $468professional $417

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$398.11
Median
$676.08
Typical High
$758.58
Aetna
Setting
Professional
Modifier
None
Typical Low
$398.11
Median
$676.08
Typical High
$758.58
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$199.53
Median
$338.84
Typical High
$380.19
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$79.43
Median
$134.90
Typical High
$151.36
BCBS Mississippi
Setting
Facility
Modifier
None
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
BCBS Mississippi
Setting
Professional
Modifier
None
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
Cigna
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$257.04
Typical High
$316.23
Cigna
Setting
Professional
Modifier
None
Typical Low
$162.18
Median
$288.40
Typical High
$630.96
United
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$446.68
United
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$204.17
Typical High
$831.76

Where Mississippi sits

The same service costs 6.5 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Mississippi· 9th of 51

$468

TX $1,122AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.