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Alpha Globin Known Family Variant Test

Missouri rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $490 · 10th–90th $363$8710%20%10th90th$490Professionalmedian $324 · 10th–90th $151$7240%10%10th90th$324$10.0$50.0$200.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$363.08
Median
$630.96
Typical High
$870.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$316.23
Median
$323.59
Typical High
$758.58
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$371.54
Typical High
$1,318.26
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$223.87
Typical High
$645.65
BCBS
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$371.54
Typical High
$416.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$724.44
Typical High
$1,202.26
Cigna
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$190.55
Typical High
$501.19
Medica
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$446.68
Typical High
$1,778.28
Medica
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$223.87
Typical High
$1,862.09
United
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$371.54
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$223.87
Typical High
$501.19