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Alpha Globin Known Family Variant Test

Minnesota rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $955 · 10th–90th $372$2,7540%20%10th90th$955Professionalmedian $372 · 10th–90th $302$5500%20%40%10th90th$372$10.0$50.0$200.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$354.81
Typical High
$1,122.02
BCBS
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$371.54
Typical High
$691.83
BCBS
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$371.54
Typical High
$371.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$741.31
Median
$1,288.25
Typical High
$3,467.37
Cigna
Setting
Professional
Modifier
Global
Typical Low
$436.52
Median
$549.54
Typical High
$776.25
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$831.76
Median
$1,202.26
Typical High
$2,754.23
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$426.58
Median
$426.58
Typical High
$724.44
Medica
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$660.69
Typical High
$1,148.15
Medica
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$223.87
Typical High
$1,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$436.52
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$371.54
Typical High
$812.83