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Alpha Globin Known Family Variant Test

Kentucky rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $372 · 10th–90th $309$8910%20%10th90th$372Professionalmedian $224 · 10th–90th $151$4370%20%10th90th$224$200.0$500.0$1.0K$2.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$309.03
Typical High
$891.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$302.00
Typical High
$446.68
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$371.54
Typical High
$398.11
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
CareSource
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$524.81
Typical High
$707.95
CareSource
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$489.78
Typical High
$616.60
Cigna
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$549.54
Typical High
$794.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$602.56
Typical High
$1,819.70
United
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$371.54
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$223.87
Typical High
$371.54