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Alpha Globin Known Family Variant Test

Illinois rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $589 · 10th–90th $324$1,0230%20%10th90th$589Professionalmedian $316 · 10th–90th $224$6920%20%10th90th$316$5.0$20.0$100.0$500.0$2.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$588.84
Typical High
$776.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$316.23
Typical High
$691.83
BCBS
Setting
Facility
Modifier
Global
Typical Low
$457.09
Median
$1,318.26
Typical High
$4,677.35
Cigna
Setting
Facility
Modifier
Global
Typical Low
$691.83
Median
$870.96
Typical High
$1,737.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$457.09
Typical High
$630.96
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$524.81
Typical High
$776.25
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$489.78
Typical High
$489.78
United
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$371.54
Typical High
$758.58
United
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$204.17
Typical High
$371.54