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Alpha Globin Known Family Variant Test

Hawaii rates for HCPCS 81258

A blood test that checks for one specific change in an alpha globin gene that has already been identified in the family. These genes make part of hemoglobin, the oxygen-carrying protein in red blood cells, and changes in them cause alpha thalassemia, an inherited form of anemia.

Rates data updated July 2026.

Facilitymedian $372 · 10th–90th $309$4470%20%40%10th90th$372Professionalmedian $468 · 10th–90th $372$6610%20%10th90th$468$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$371.54
Typical High
$446.68
Aetna
Setting
Professional
Modifier
Global
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$204.17
Typical High
$446.68
HMSA
Setting
Professional
Modifier
Global
Typical Low
$371.54
Median
$467.74
Typical High
$512.86
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$416.87
Median
$446.68
Typical High
$562.34
United
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$371.54
Typical High
$446.68
University Health Alliance
Setting
Professional
Modifier
Global
Typical Low
$316.23
Median
$549.54
Typical High
$851.14