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Lyme Disease Bacterial Protein Urine Test

South Dakota rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

How much does Lyme Disease Bacterial Protein Urine Test cost?

$21.38

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $21.38 for this service. The price depends on where it is billed: about $24.55 from a physician practice, and about $21.38 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$24.55$14.45 to $43.65
FacilityA hospital or hospital-owned outpatient department$21.38$17.78 to $21.38

How much rates vary

Facilitymedian $21 · 10th to 90th $13 to $34Professionalmedian $25 · 10th to 90th $13 to $45
$10.0$20.0$50.0$100.0facility $21professional $25

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$13.18
Median
$21.38
Typical High
$21.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$14.45
Typical High
$17.38
Cigna
Setting
Professional
Modifier
Global
Typical Low
$26.92
Median
$35.48
Typical High
$44.67
Medica
Setting
Facility
Modifier
Global
Typical Low
$17.78
Median
$17.78
Typical High
$89.13
Medica
Setting
Professional
Modifier
Global
Typical Low
$9.55
Median
$9.55
Typical High
$22.39
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$26.92
Median
$43.65
Typical High
$51.29
United
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$22.39
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$11.22
Typical High
$24.55
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$18.62

Where South Dakota sits

The same service costs 2.3 times more in North Dakota than in Connecticut. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Dakota $21.38 · 6th of 51
ND $28.18CT $12.30

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.