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Lyme Disease Bacterial Protein Urine Test

South Carolina rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $46 · 10th–90th $14$890%10%20%10th90th$46Professionalmedian $14 · 10th–90th $14$160%50%90th$14$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$14.45
Median
$45.71
Typical High
$89.13
Aetna
Setting
Professional
Modifier
Global
Typical Low
$14.45
Median
$14.45
Typical High
$14.79
BCBS
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$19.95
Typical High
$26.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$12.88
Median
$47.86
Typical High
$107.15
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$21.38
Typical High
$26.92
Medcost
Setting
Facility
Modifier
Global
Typical Low
$13.18
Median
$15.85
Typical High
$24.55
United
Setting
Facility
Modifier
Global
Typical Low
$10.23
Median
$18.62
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$11.22
Typical High
$22.39