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Lyme Disease Bacterial Protein Urine Test

Pennsylvania rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $36 · 10th–90th $16$660%10%10th90th$36Professionalmedian $15 · 10th–90th $11$190%20%40%10th90th$15$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$15.85
Median
$36.31
Typical High
$66.07
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.30
Median
$15.14
Typical High
$17.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$14.45
Median
$14.45
Typical High
$14.45
Cigna
Setting
Facility
Modifier
Global
Typical Low
$13.49
Median
$25.70
Typical High
$63.10
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$21.38
Typical High
$26.92
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$8.71
Median
$10.96
Typical High
$26.92
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$18.62
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$14.13
Median
$16.22
Typical High
$32.36
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$21.88
Median
$38.90
Typical High
$66.07
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$12.30
Median
$15.14
Typical High
$54.95
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$45.71
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$16.60
Median
$18.62
Typical High
$19.05
United
Setting
Facility
Modifier
Global
Typical Low
$9.33
Median
$18.62
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$11.75
Typical High
$28.18