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Lyme Disease Bacterial Protein Urine Test

Nebraska rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $30 · 10th–90th $11$580%20%10th90th$30Professionalmedian $12 · 10th–90th $11$310%50%10th90th$12$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$13.18
Median
$48.98
Typical High
$93.33
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.30
Median
$12.30
Typical High
$12.30
BCBS
Setting
Facility
Modifier
Global
Typical Low
$28.18
Median
$36.31
Typical High
$70.79
BCBS
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$28.84
Typical High
$30.90
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$35.48
Typical High
$44.67
Medica
Setting
Facility
Modifier
Global
Typical Low
$6.76
Median
$12.30
Typical High
$89.13
Medica
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$11.22
Typical High
$20.42
United
Setting
Facility
Modifier
Global
Typical Low
$7.76
Median
$16.98
Typical High
$18.62
United
Setting
Professional
Modifier
Global
Typical Low
$10.72
Median
$11.22
Typical High
$37.15