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Lyme Disease Bacterial Protein Urine Test

North Carolina rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $15 · 10th–90th $10$890%20%10th90th$15Professionalmedian $15 · 10th–90th $11$150%50%10th$15$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$14.79
Median
$14.79
Typical High
$40.74
Aetna
Setting
Professional
Modifier
Global
Typical Low
$13.49
Median
$14.79
Typical High
$14.79
BCBS
Setting
Facility
Modifier
Global
Typical Low
$41.69
Median
$41.69
Typical High
$58.88
BCBS
Setting
Professional
Modifier
Global
Typical Low
$12.02
Median
$16.98
Typical High
$18.62
Cigna
Setting
Facility
Modifier
Global
Typical Low
$15.49
Median
$48.98
Typical High
$85.11
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$22.91
Typical High
$28.18
Medcost
Setting
Facility
Modifier
Global
Typical Low
$9.77
Median
$13.80
Typical High
$19.50
Medcost
Setting
Professional
Modifier
Global
Typical Low
$12.02
Median
$12.02
Typical High
$14.13
United
Setting
Facility
Modifier
Global
Typical Low
$9.33
Median
$18.62
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$8.32
Median
$9.33
Typical High
$18.62
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$89.13
Median
$89.13
Typical High
$89.13