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Lyme Disease Bacterial Protein Urine Test

Missouri rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $30 · 10th–90th $18$360%20%10th90th$30Professionalmedian $17 · 10th–90th $8$320%10%20%10th90th$17$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$18.20
Median
$32.36
Typical High
$36.31
Aetna
Setting
Professional
Modifier
Global
Typical Low
$16.22
Median
$18.20
Typical High
$36.31
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$7.59
Median
$12.88
Typical High
$29.51
Cigna
Setting
Facility
Modifier
Global
Typical Low
$26.30
Median
$38.90
Typical High
$97.72
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$21.38
Typical High
$26.92
Medica
Setting
Facility
Modifier
Global
Typical Low
$16.22
Median
$32.36
Typical High
$89.13
Medica
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$11.22
Typical High
$20.42
United
Setting
Facility
Modifier
Global
Typical Low
$8.32
Median
$18.62
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$11.22
Typical High
$22.39