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Lyme Disease Bacterial Protein Urine Test

Minnesota rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $50 · 10th–90th $19$1380%20%10th90th$50Professionalmedian $19 · 10th–90th $15$280%20%10th90th$19$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$17.38
Median
$17.38
Typical High
$17.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.02
Median
$14.45
Typical High
$22.39
BCBS
Setting
Facility
Modifier
Global
Typical Low
$18.20
Median
$18.62
Typical High
$18.62
BCBS
Setting
Professional
Modifier
Global
Typical Low
$14.79
Median
$18.62
Typical High
$18.62
Cigna
Setting
Facility
Modifier
Global
Typical Low
$40.74
Median
$63.10
Typical High
$173.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$27.54
Typical High
$38.02
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$48.98
Median
$60.26
Typical High
$138.04
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$21.38
Typical High
$35.48
Medica
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$29.51
Typical High
$89.13
Medica
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$11.22
Typical High
$39.81
United
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$21.38
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$18.62
Typical High
$41.69