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Lyme Disease Bacterial Protein Urine Test

Michigan rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $18 · 10th–90th $17$320%50%10th90th$18Professionalmedian $15 · 10th–90th $11$220%20%10th90th$15$5.0$10.0$20.0$50.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$17.78
Median
$17.78
Typical High
$32.36
Aetna
Setting
Professional
Modifier
Global
Typical Low
$15.14
Median
$17.78
Typical High
$22.39
BCBS
Setting
Facility
Modifier
Global
Typical Low
$13.18
Median
$13.18
Typical High
$13.18
BCBS
Setting
Professional
Modifier
Global
Typical Low
$12.30
Median
$13.18
Typical High
$13.18
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$22.91
Typical High
$28.18
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$19.05
Typical High
$46.77
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$15.14
Median
$18.62
Typical High
$25.12
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$21.38
Typical High
$22.91
United
Setting
Facility
Modifier
Global
Typical Low
$11.22
Median
$18.62
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$11.22
Typical High
$18.62