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Lyme Disease Bacterial Protein Urine Test

Maine rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $30 · 10th–90th $19$1200%20%40%10th90th$30Professionalmedian $15 · 10th–90th $9$220%20%10th90th$15$5.0$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$46.77
Aetna
Setting
Professional
Modifier
Global
Typical Low
$14.13
Median
$15.14
Typical High
$15.14
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$102.33
Median
$120.23
Typical High
$128.82
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$7.41
Median
$10.72
Typical High
$18.62
Cigna
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$42.66
Typical High
$42.66
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$21.38
Typical High
$26.92
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$18.62
Typical High
$22.39
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$46.77
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$14.13
Median
$15.14
Typical High
$18.62
United
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$18.62
Typical High
$32.36