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Lyme Disease Bacterial Protein Urine Test

Illinois rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $30 · 10th–90th $19$400%10%20%10th90th$30Professionalmedian $16 · 10th–90th $11$380%10%20%10th90th$16$5.0$10.0$20.0$50.0$100.0$200.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$18.20
Median
$29.51
Typical High
$39.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.30
Median
$16.22
Typical High
$38.02
BCBS
Setting
Facility
Modifier
Global
Typical Low
$22.39
Median
$25.12
Typical High
$30.20
Cigna
Setting
Facility
Modifier
Global
Typical Low
$21.88
Median
$40.74
Typical High
$95.50
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$22.91
Typical High
$28.18
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$26.30
Typical High
$151.36
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$23.99
Median
$23.99
Typical High
$23.99
Molina
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$13.18
Typical High
$13.18
United
Setting
Facility
Modifier
Global
Typical Low
$14.13
Median
$18.62
Typical High
$37.15
United
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$11.22
Typical High
$18.62