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Lyme Disease Bacterial Protein Urine Test

Iowa rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $29 · 10th–90th $14$540%10%20%10th90th$29Professionalmedian $14 · 10th–90th $11$430%20%10th90th$14$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$14.45
Median
$43.65
Typical High
$53.70
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.30
Median
$14.45
Typical High
$14.45
Cigna
Setting
Professional
Modifier
Global
Typical Low
$26.92
Median
$35.48
Typical High
$44.67
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$15.85
Median
$23.99
Typical High
$33.88
Medica
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$22.39
Typical High
$51.29
Medica
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$11.22
Typical High
$46.77
United
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$41.69
United
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$11.22
Typical High
$40.74
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$14.79
Median
$18.62
Typical High
$18.62