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Lyme Disease Bacterial Protein Urine Test

Florida rates for HCPCS 0316U

Tests for Lyme disease by looking directly for OspA, a protein made by the Borrelia burgdorferi bacterium, in a urine sample, and reports whether it is found. Unlike most Lyme testing, it detects a protein made by the bacterium itself rather than the antibodies your immune system makes against it or the bacterium's genetic material.

Rates data updated July 2026.

Facilitymedian $35 · 10th–90th $13$1000%10%10th90th$35Professionalmedian $12 · 10th–90th $11$140%50%10th90th$12$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$13.49
Median
$51.29
Typical High
$109.65
Aetna
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$12.02
Typical High
$14.13
AvMed
Setting
Facility
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$18.62
AvMed
Setting
Professional
Modifier
Global
Typical Low
$14.79
Median
$18.62
Typical High
$18.62
Cigna
Setting
Facility
Modifier
Global
Typical Low
$9.55
Median
$14.45
Typical High
$75.86
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$26.92
Typical High
$89.13
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$34.67
Median
$34.67
Typical High
$34.67
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$11.22
Typical High
$16.98
United
Setting
Facility
Modifier
Global
Typical Low
$7.76
Median
$16.98
Typical High
$18.62
United
Setting
Professional
Modifier
Global
Typical Low
$6.46
Median
$7.76
Typical High
$18.62
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$7.59
Median
$9.77
Typical High
$18.62