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Colorectal Cancer Two-Gene Methylation Test

Pennsylvania rates for HCPCS 0229U

Used in colorectal (bowel) cancer to check two genes, BCAT1 and IKZF1, for methylation — chemical tags that switch a gene off. It looks at whether these two genes have been silenced in this way, not at whether their DNA spelling has changed.

Rates data updated June 2026.

Facilitymedian $562 · 10th–90th $245$1,5850%5%10%10th90th$562Professionalmedian $162 · 10th–90th $107$3630%10%20%10th90th$162$100.0$200.0$500.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$562.34
Typical High
$1,584.89
Aetna
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$158.49
Typical High
$354.81
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$302.00
Typical High
$302.00
Cigna
Setting
Facility
Modifier
Global
Typical Low
$204.17
Median
$512.86
Typical High
$1,122.02
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,862.09
Median
$1,862.09
Typical High
$1,862.09
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$338.84
Median
$501.19
Typical High
$549.54
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$380.19
Median
$380.19
Typical High
$380.19
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$380.19
Typical High
$676.08
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$162.18
Median
$371.54
Typical High
$676.08
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$154.88
Typical High
$354.81
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$380.19
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$380.19
Typical High
$380.19
United
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$380.19
Typical High
$457.09
United
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$114.82
Typical High
$346.74