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Colorectal Cancer Two-Gene Methylation Test

Nationwide rates for HCPCS 0229U

Used in colorectal (bowel) cancer to check two genes, BCAT1 and IKZF1, for methylation — chemical tags that switch a gene off. It looks at whether these two genes have been silenced in this way, not at whether their DNA spelling has changed.

Rates data updated June 2026.

Facilitymedian $490 · 10th–90th $191$1,3490%10%10th90th$490Professionalmedian $186 · 10th–90th $105$4070%10%10th90th$186$0.2$2.0$20.0$200.0$2.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$549.54
Typical High
$1,230.27
Aetna
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$181.97
Typical High
$363.08
BCBS
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$512.86
Typical High
$1,737.80
BCBS
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$37.15
Typical High
$323.59
Cigna
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$707.95
Typical High
$1,698.24
Cigna
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$562.34
Typical High
$1,047.13
United
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$229.09
Typical High
$457.09
United
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$114.82
Typical High
$354.81