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Colorectal Cancer Two-Gene Methylation Test

Missouri rates for HCPCS 0229U

Used in colorectal (bowel) cancer to check two genes, BCAT1 and IKZF1, for methylation — chemical tags that switch a gene off. It looks at whether these two genes have been silenced in this way, not at whether their DNA spelling has changed.

Rates data updated July 2026.

How much does Colorectal Cancer Two-Gene Methylation Test cost?

$245

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $245 for this service. The price depends on where it is billed: about $117 from a physician practice, and about $617 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$117$33.11 to $257
FacilityA hospital or hospital-owned outpatient department$617$447 to $661

How much rates vary

Facilitymedian $617 · 10th to 90th $363 to $741Professionalmedian $117 · 10th to 90th $33 to $631
$50$100$200$500$1Kfacility $617professional $117

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$660.69
Typical High
$741.31
Aetna
Setting
Professional
Modifier
Global
Typical Low
$602.56
Median
$645.65
Typical High
$1,318.26
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$34.67
Typical High
$389.05
Cigna
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$812.83
Typical High
$1,995.26
Medica
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$457.09
Typical High
$1,819.70
Medica
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$114.82
Typical High
$1,905.46
United
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$380.19
Typical High
$457.09
United
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$114.82
Typical High
$354.81

Where Missouri sits

The same service costs 19.5 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 21st of 51

$245

AK $871KY $44.67

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.