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PIK3CA Testing On A Blood Plasma Sample

South Dakota rates for HCPCS 0177U

A breast cancer test that examines plasma, the liquid part of a blood sample, for 11 specific changes in the PIK3CA gene. The result states whether any of those changes were found. Because the test works from a blood draw, no tumor tissue has to be removed; a companion version looks for the same 11 changes in tumor tissue.

Rates data updated July 2026.

How much does PIK3CA Testing On A Blood Plasma Sample cost?

$417

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $417 for this service. The price depends on where it is billed: about $331 from a physician practice, and about $525 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$331$214 to $646
FacilityA hospital or hospital-owned outpatient department$525$525 to $525

How much rates vary

Facilitymedian $525 · 10th to 90th $309 to $525Professionalmedian $331 · 10th to 90th $186 to $661
$200$500facility $525professional $331

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$316.23
Typical High
$316.23
Aetna
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$213.80
Typical High
$257.04
Cigna
Setting
Facility
Modifier
Global
Typical Low
$524.81
Median
$524.81
Typical High
$524.81
Cigna
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$524.81
Typical High
$660.69
Medica
Setting
Facility
Modifier
Global
Typical Low
$257.04
Median
$309.03
Typical High
$501.19
Medica
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$125.89
Typical High
$1,380.38
Midlands
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$331.13
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$389.05
Median
$645.65
Typical High
$758.58
United
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$147.91
Typical High
$363.08
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$275.42
Typical High
$275.42

Where South Dakota sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 2nd of 51

$417

AK $617NE $182

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.