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PIK3CA Testing On A Blood Plasma Sample

Nationwide rates for HCPCS 0177U

A breast cancer test that examines plasma, the liquid part of a blood sample, for 11 specific changes in the PIK3CA gene. The result states whether any of those changes were found. Because the test works from a blood draw, no tumor tissue has to be removed; a companion version looks for the same 11 changes in tumor tissue.

Rates data updated June 2026.

Facilitymedian $427 · 10th–90th $219$1,2590%10%10th90th$427Professionalmedian $219 · 10th–90th $135$3310%20%10th90th$219$0.5$5.0$50.0$500.0$5.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$478.63
Typical High
$1,202.26
Aetna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$218.78
Typical High
$302.00
BCBS
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$467.74
Typical High
$1,380.38
BCBS
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$134.90
Typical High
$346.74
Cigna
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$537.03
Typical High
$1,230.27
Cigna
Setting
Professional
Modifier
Global
Typical Low
$316.23
Median
$398.11
Typical High
$758.58
United
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$275.42
Typical High
$331.13
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$147.91
Typical High
$309.03