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Lisocabtagene Maraleucel (Breyanzi) CAR-T Therapy

South Dakota rates for HCPCS Q2054

Lisocabtagene maraleucel, up to 110 million autologous anti-CD19 CAR-positive viable T cells, including leukapheresis and dose preparation procedures, per therapeutic dose

Rates data updated October 2026.

How much does Breyanzi (lisocabtagene maraleucel) cost?

$575,440

Typical physician fee. In South Dakota, October 2026.

Insurers have agreed to pay about $575,440 for this service. Most negotiated rates run $562,341 to $676,083.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $870,964 · 10th to 90th $676,083 to $870,964Professionalmedian $575,440 · 10th to 90th $549,541 to $851,138
$1Mfacility $870,964professional $575,440

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$575,439.94
Median
$575,439.94
Typical High
$676,082.98
Aetna
Setting
Professional
Modifier
None
Typical Low
$575,439.94
Median
$575,439.94
Typical High
$676,082.98
Cigna
Setting
Professional
Modifier
None
Typical Low
$549,540.87
Median
$549,540.87
Typical High
$676,082.98
Medica
Setting
Facility
Modifier
None
Typical Low
$741,310.24
Median
$870,963.59
Typical High
$870,963.59
Medica
Setting
Professional
Modifier
None
Typical Low
$562,341.33
Median
$977,237.22
Typical High
$977,237.22
Midlands
Setting
Professional
Modifier
None
Typical Low
$562,341.33
Median
$562,341.33
Typical High
$588,843.66
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$630,957.34
Median
$630,957.34
Typical High
$630,957.34
United
Setting
Professional
Modifier
None
Typical Low
$562,341.33
Median
$758,577.58
Typical High
$851,138.04
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$288,403.15
Median
$288,403.15
Typical High
$331,131.12
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$114,815.36
Median
$114,815.36
Typical High
$134,896.29
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$87,096.36
Median
$87,096.36
Typical High
$100,000.00
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$57,543.99
Median
$57,543.99
Typical High
$67,608.30

Where South Dakota sits

The same service costs 1.7 times more in Texas than in Minnesota. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 26th of 51

$575,440

TX $977,237MN $562,341

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.