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Sipuleucel-T (Provenge) Autologous Cell Infusion

Massachusetts rates for HCPCS Q2043

Sipuleucel-T, minimum of 50 million autologous CD54+ cells activated with PAP-GM-CSF, including leukapheresis and all other preparatory procedures, per infusion

Rates data updated July 2026.

How much does Provenge (sipuleucel-t) cost?

$56,234

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $56,234 for this service. The price depends on where it is billed: about $56,234 from a physician practice, and about $56,234 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$56,234$56,234 to $56,234
FacilityA hospital or hospital-owned outpatient department$56,234$56,234 to $77,625

How much rates vary

Facilitymedian $56,234 · 10th to 90th $56,234 to $125,893Professionalmedian $56,234 · 10th to 90th $54,954 to $61,660
$5K$10K$20K$50K$100K$200Kfacility $56,234professional $56,234

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$56,234.13
Median
$56,234.13
Typical High
$56,234.13
Aetna
Setting
Professional
Modifier
Global
Typical Low
$56,234.13
Median
$56,234.13
Typical High
$61,659.50
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$53,703.18
Median
$154,881.66
Typical High
$281,838.29
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$54,954.09
Median
$56,234.13
Typical High
$239,883.29
BCBS
Setting
Facility
Modifier
Global
Typical Low
$56,234.13
Median
$56,234.13
Typical High
$112,201.85
Cigna
Setting
Facility
Modifier
Global
Typical Low
$54,954.09
Median
$102,329.30
Typical High
$245,470.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$56,234.13
Median
$56,234.13
Typical High
$56,234.13
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$3,630.78
Median
$67,608.30
Typical High
$87,096.36
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$83,176.38
Median
$83,176.38
Typical High
$97,723.72
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$56,234.13
Median
$56,234.13
Typical High
$57,543.99
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$53,703.18
Median
$154,881.66
Typical High
$281,838.29
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$54,954.09
Median
$56,234.13
Typical High
$239,883.29
United
Setting
Facility
Modifier
Global
Typical Low
$56,234.13
Median
$56,234.13
Typical High
$120,226.44
United
Setting
Professional
Modifier
Global
Typical Low
$52,480.75
Median
$54,954.09
Typical High
$60,255.96

Where Massachusetts sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 47th of 51

$56,234

MN $63,096NY $53,703

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.