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Tixagevimab and Cilgavimab Injection, Home or Residence

California rates for HCPCS M0221

Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known SARS-CoV-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available COVID-19 vaccine is not recommended due to a history of severe adverse reaction to a COVID-19 vaccine(s) and/or COVID-19 vaccine component(s), includes injection and post administration monitoring in the home or residence; this includes a beneficiary's home that has been made provider-based to the hospital during the COVID-19 public health emergency

Rates data updated July 2026.

How much does Tixagevimab and Cilgavimab Injection, Home or Residence cost?

$1,549

Typical facility fee. In California, July 2026.

Insurers have agreed to pay about $1,549 for this service. Most negotiated rates run $447 to $1,549.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 3 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $1,549 · 10th to 90th $1,549 to $1,549Professionalmedian $447 · 10th to 90th $302 to $708
$500.0$1.0Kfacility $1,549professional $447

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$707.95
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$1,548.82
Median
$1,548.82
Typical High
$1,548.82
United
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$295.12
Typical High
$295.12

Where California sits

The same service costs 24.0 times more in New Jersey than in Pennsylvania. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

California $1,549 · 6th of 32
NJ $5,623PA $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.