Tixagevimab and Cilgavimab Injection, Home or Residence

California rates for HCPCS M0221

Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known SARS-CoV-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available COVID-19 vaccine is not recommended due to a history of severe adverse reaction to a COVID-19 vaccine(s) and/or COVID-19 vaccine component(s), includes injection and post administration monitoring in the home or residence; this includes a beneficiary's home that has been made provider-based to the hospital during the COVID-19 public health emergency

Rates data updated October 2026.

How much rates vary

Professionalmedian $447 · 10th to 90th $302 to $708

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Kaiser Permanente Setting Professional Modifier None Typical Low $309.03 Median $446.68 Typical High $691.83	Professional	None	$309.03	$446.68	$691.83
United Setting Professional Modifier None Typical Low $295.12 Median $295.12 Typical High $1,148.15	Professional	None	$295.12	$295.12	$1,148.15