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Tixagevimab and Cilgavimab Injection, Home or Residence

Nationwide rates for HCPCS M0221

Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known SARS-CoV-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available COVID-19 vaccine is not recommended due to a history of severe adverse reaction to a COVID-19 vaccine(s) and/or COVID-19 vaccine component(s), includes injection and post administration monitoring in the home or residence; this includes a beneficiary's home that has been made provider-based to the hospital during the COVID-19 public health emergency

Rates data updated July 2026.

Facilitymedian $251 · 10th–90th $251$7760%50%90th$251Professionalmedian $251 · 10th–90th $251$4680%50%90th$251$100.0$200.0$500.0$1.0K$2.0K$5.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
BCBS
Setting
Facility
Modifier
Global
Typical Low
$776.25
Median
$1,995.26
Typical High
$3,890.45
Cigna
Setting
Facility
Modifier
Global
Typical Low
$251.19
Median
$251.19
Typical High
$316.23
Cigna
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$269.15
Typical High
$316.23
United
Setting
Facility
Modifier
Global
Typical Low
$60.26
Median
$251.19
Typical High
$1,258.93
United
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$288.40
Typical High
$501.19