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Fam-Trastuzumab Deruxtecan-nxki Injection

North Carolina rates for HCPCS J9358 · Enhertu

Injection, fam-trastuzumab deruxtecan-nxki, 1 mg

Rates data updated October 2026.

How much does Enhertu (fam-trastuzumab deruxtecan-nxki) cost?

$33.11per mg

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $33.11 for each mg of this drug. The price depends on where it is billed: about $33.11 from a physician practice, and about $46.77 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$33.11
At a hospital outpatient department
$46.77

The same drug, in the same amount, costs 41% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$33.11$33.11 to $34.67
FacilityA hospital or hospital-owned outpatient department$46.77$38.02 to $64.57

How much rates vary

Facilitymedian $47 · 10th to 90th $26 to $69Professionalmedian $33 · 10th to 90th $31 to $39
$20$50facility $47professional $33

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$25.70
Median
$25.70
Typical High
$64.57
Aetna
Setting
Professional
Modifier
None
Typical Low
$25.70
Median
$25.70
Typical High
$34.67
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$38.90
Median
$60.26
Typical High
$69.18
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$33.11
Typical High
$38.90
Cigna
Setting
Facility
Modifier
None
Typical Low
$46.77
Median
$52.48
Typical High
$74.13
Cigna
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$33.11
Typical High
$33.11
Medcost
Setting
Facility
Modifier
None
Typical Low
$25.70
Median
$25.70
Typical High
$38.90
Medcost
Setting
Professional
Modifier
None
Typical Low
$25.70
Median
$25.70
Typical High
$38.90
United
Setting
Professional
Modifier
None
Typical Low
$30.90
Median
$33.11
Typical High
$33.11
6 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$12.88
Median
$12.88
Typical High
$16.98
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$5.13
Median
$5.13
Typical High
$6.76
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$3.80
Median
$3.80
Typical High
$5.13
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$2.57
Median
$2.57
Typical High
$3.39
Ambetter
Setting
Professional
Modifier
JW · Drug discarded
Typical Low
$33.11
Median
$33.11
Typical High
$37.15
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$12.88
Median
$12.88
Typical High
$12.88

Where North Carolina sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 40th of 51

$33.11

AK $41.69AZ $33.11

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.