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Fam-Trastuzumab Deruxtecan-nxki Injection

Illinois rates for HCPCS J9358 · Enhertu

Injection, fam-trastuzumab deruxtecan-nxki, 1 mg

Rates data updated October 2026.

How much does Enhertu (fam-trastuzumab deruxtecan-nxki) cost?

$33.11per mg

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $33.11 for each mg of this drug. The price depends on where it is billed: about $33.11 from a physician practice, and about $64.57 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$33.11
At a hospital outpatient department
$64.57

The same drug, in the same amount, costs 95% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$33.11$33.11 to $34.67
FacilityA hospital or hospital-owned outpatient department$64.57$45.71 to $81.28

How much rates vary

Facilitymedian $65 · 10th to 90th $33 to $110Professionalmedian $33 · 10th to 90th $31 to $39
$50$100$200facility $65professional $33

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$33.11
Median
$45.71
Typical High
$64.57
Aetna
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$33.11
Typical High
$51.29
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$16.60
Median
$16.60
Typical High
$16.60
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$6.61
Median
$6.61
Typical High
$6.61
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$4.90
Median
$4.90
Typical High
$5.01
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$3.31
Median
$3.31
Typical High
$3.31
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$72.44
Median
$104.71
Typical High
$275.42
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$32.36
Median
$37.15
Typical High
$37.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$44.67
Median
$66.07
Typical High
$81.28
Cigna
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$33.11
Typical High
$33.88
Hally Health
Setting
Professional
Modifier
None
Typical Low
$29.51
Median
$37.15
Typical High
$74.13
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$38.90
Typical High
$38.90
Molina
Setting
Professional
Modifier
None
Typical Low
$30.90
Median
$38.90
Typical High
$45.71
United
Setting
Facility
Modifier
None
Typical Low
$33.11
Median
$33.11
Typical High
$74.13
United
Setting
Professional
Modifier
None
Typical Low
$30.90
Median
$33.88
Typical High
$35.48
1 more rate with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Ambetter
Setting
Professional
Modifier
JZ · No drug discarded
Typical Low
$30.90
Median
$30.90
Typical High
$31.62

Where Illinois sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 20th of 51

$33.11

AK $41.69AZ $33.11

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.