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Trastuzumab and Hyaluronidase-oysk Injection

South Dakota rates for HCPCS J9356 · Herceptin Hylecta

Injection, trastuzumab, 10 mg and hyaluronidase-oysk

Rates data updated October 2026.

How much does Herceptin Hylecta (trastuzumab and hyaluronidase-oysk) cost?

$66.07

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $66.07 for this service. The price depends on where it is billed: about $66.07 from a physician practice, and about $66.07 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$66.07$60.26 to $95.50
FacilityA hospital or hospital-owned outpatient department$66.07$66.07 to $93.33

How much rates vary

Facilitymedian $66 · 10th to 90th $66 to $107Professionalmedian $66 · 10th to 90th $59 to $95
$100$200facility $66professional $66

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$93.33
Aetna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$93.33
Cigna
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$74.13
Typical High
$74.13
Cigna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$74.13
Typical High
$95.50
Medica
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$107.15
Typical High
$107.15
Medica
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$70.79
Typical High
$302.00
Midlands
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$95.50
Typical High
$95.50
Midlands
Setting
Professional
Modifier
None
Typical Low
$93.33
Median
$93.33
Typical High
$93.33
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$64.57
Median
$64.57
Typical High
$64.57
United
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$63.10
Typical High
$70.79
Wellmark
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
Wellmark
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$28.84
Median
$28.84
Typical High
$46.77
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$11.75
Median
$11.75
Typical High
$18.62
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$8.71
Median
$8.71
Typical High
$14.13
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$5.89
Median
$5.89
Typical High
$9.33

Where South Dakota sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 9th of 51

$66.07

AK $79.43GA $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.