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Trastuzumab and Hyaluronidase-oysk Injection

Missouri rates for HCPCS J9356 · Herceptin Hylecta

Injection, trastuzumab, 10 mg and hyaluronidase-oysk

Rates data updated October 2026.

How much does Herceptin Hylecta (trastuzumab and hyaluronidase-oysk) cost?

$64.57

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $64.57 for this service. The price depends on where it is billed: about $64.57 from a physician practice, and about $93.33 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$64.57$58.88 to $93.33
FacilityA hospital or hospital-owned outpatient department$93.33$67.61 to $151

How much rates vary

Facilitymedian $93 · 10th to 90th $60 to $209Professionalmedian $65 · 10th to 90th $59 to $302
$100$200facility $93professional $65

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$60.26
Median
$91.20
Typical High
$128.82
Aetna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$60.26
Typical High
$93.33
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$81.28
Typical High
$208.93
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$74.13
Typical High
$93.33
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$64.57
Median
$64.57
Typical High
$158.49
Cigna
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$128.82
Typical High
$151.36
Cigna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
Medica
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$93.33
Typical High
$371.54
Medica
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$302.00
Typical High
$302.00
United
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
United
Setting
Professional
Modifier
None
Typical Low
$53.70
Median
$63.10
Typical High
$70.79
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$28.84
Median
$30.20
Typical High
$46.77
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$11.75
Median
$12.02
Typical High
$18.62
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$8.71
Median
$8.91
Typical High
$14.13
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$5.89
Median
$6.03
Typical High
$9.33
Ambetter
Setting
Professional
Modifier
JZ · No drug discarded
Typical Low
$60.26
Median
$60.26
Typical High
$63.10

Where Missouri sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 10th of 51

$64.57

AK $79.43GA $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.