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Trastuzumab and Hyaluronidase-oysk Injection

Minnesota rates for HCPCS J9356 · Herceptin Hylecta

Injection, trastuzumab, 10 mg and hyaluronidase-oysk

Rates data updated October 2026.

How much does Herceptin Hylecta (trastuzumab and hyaluronidase-oysk) cost?

$60.26

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $60.26 for this service. The price depends on where it is billed: about $60.26 from a physician practice, and about $74.13 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$60.26$58.88 to $66.07
FacilityA hospital or hospital-owned outpatient department$74.13$58.88 to $100

How much rates vary

Facilitymedian $74 · 10th to 90th $59 to $123Professionalmedian $60 · 10th to 90th $59 to $76
$100$200facility $74professional $60

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
Aetna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$63.10
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$100.00
Typical High
$123.03
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$61.66
Typical High
$63.10
Cigna
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$79.43
Typical High
$93.33
Cigna
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$61.66
Typical High
$75.86
Health Partners
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$74.13
Typical High
$74.13
Health Partners
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
Medica
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$107.15
Typical High
$120.23
Medica
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$70.79
Typical High
$302.00
United
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
United
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$63.10
Typical High
$97.72
8 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$28.84
Median
$28.84
Typical High
$28.84
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$11.75
Median
$11.75
Typical High
$11.75
Aetna
Setting
Facility
Modifier
55 · Aftercare only
Typical Low
$8.71
Median
$8.71
Typical High
$8.71
Aetna
Setting
Facility
Modifier
56 · Pre-op care only
Typical Low
$5.89
Median
$5.89
Typical High
$5.89
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$28.84
Median
$28.84
Typical High
$30.20
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$11.75
Median
$11.75
Typical High
$12.02
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$8.71
Median
$8.71
Typical High
$8.91
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$5.89
Median
$5.89
Typical High
$6.03

Where Minnesota sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 20th of 51

$60.26

AK $79.43GA $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.