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Asparaginase (Rylaze) Injection

Virginia rates for HCPCS J9021

Injection, asparaginase, recombinant, (Rylaze), 0.1 mg

Rates data updated October 2026.

How much does Rylaze cost?

$58.88per 0.1 mg

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $58.88 for each 0.1 mg of this drug. The price depends on where it is billed: about $58.88 from a physician practice, and about $102 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 0.1 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$58.88
At a hospital outpatient department
$102

The same drug, in the same amount, costs 74% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$58.88$58.88 to $60.26
FacilityA hospital or hospital-owned outpatient department$102$58.88 to $141

How much rates vary

Facilitymedian $102 · 10th to 90th $56 to $170Professionalmedian $59 · 10th to 90th $56 to $63
$50$100$200facility $102professional $59

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$61.66
Typical High
$109.65
Aetna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$61.66
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$56.23
Median
$120.23
Typical High
$190.55
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
CareFirst
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$56.23
Typical High
$56.23
Cigna
Setting
Facility
Modifier
None
Typical Low
$85.11
Median
$120.23
Typical High
$151.36
Cigna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$58.88
Typical High
$67.61
Medcost
Setting
Facility
Modifier
None
Typical Low
$56.23
Median
$56.23
Typical High
$93.33
Medcost
Setting
Professional
Modifier
None
Typical Low
$41.69
Median
$41.69
Typical High
$67.61
Sentara
Setting
Facility
Modifier
None
Typical Low
$53.70
Median
$60.26
Typical High
$77.62
Sentara
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$63.10
United
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
United
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$60.26
Typical High
$63.10

Where Virginia sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 41st of 51

$58.88

AK $72.44LA $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.