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Asparaginase (Rylaze) Injection

South Carolina rates for HCPCS J9021

Injection, asparaginase, recombinant, (Rylaze), 0.1 mg

Rates data updated October 2026.

How much does Rylaze cost?

$58.88per 0.1 mg

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $58.88 for each 0.1 mg of this drug. The price depends on where it is billed: about $58.88 from a physician practice, and about $60.26 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 0.1 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$58.88
At a hospital outpatient department
$60.26

The same drug, in the same amount, costs 2% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$58.88$58.88 to $61.66
FacilityA hospital or hospital-owned outpatient department$60.26$56.23 to $83.18

How much rates vary

Facilitymedian $60 · 10th to 90th $43 to $117Professionalmedian $59 · 10th to 90th $48 to $63
$50$100facility $60professional $59

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$61.66
Typical High
$61.66
Aetna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$61.66
Typical High
$61.66
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$40.74
Median
$60.26
Typical High
$104.71
BCBS South Carolina
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$63.10
Cigna
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$102.33
Typical High
$144.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
Medcost
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$74.13
Typical High
$151.36
Medcost
Setting
Professional
Modifier
None
Typical Low
$41.69
Median
$41.69
Typical High
$67.61
Molina
Setting
Professional
Modifier
None
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
United
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$125.89
United
Setting
Professional
Modifier
None
Typical Low
$44.67
Median
$56.23
Typical High
$60.26
1 more rate with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$20.89
Median
$20.89
Typical High
$36.31

Where South Carolina sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 38th of 51

$58.88

AK $72.44LA $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.