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Asparaginase (Rylaze) Injection

Pennsylvania rates for HCPCS J9021

Injection, asparaginase, recombinant, (Rylaze), 0.1 mg

Rates data updated July 2026.

How much does Rylaze cost?

$56.23per 0.1 mg

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $56.23 for each 0.1 mg of this drug. The price depends on where it is billed: about $56.23 from a physician practice, and about $85.11 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 0.1 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$56.23
At a hospital outpatient department
$85.11

The same drug, in the same amount, costs 51% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$56.23$56.23 to $58.88
FacilityA hospital or hospital-owned outpatient department$85.11$64.57 to $135

How much rates vary

Facilitymedian $85 · 10th to 90th $56 to $158Professionalmedian $56 · 10th to 90th $56 to $63
$50$100$200facility $85professional $56

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$87.10
Typical High
$154.88
Aetna
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$61.66
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$61.66
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
Cigna
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$93.33
Typical High
$208.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$57.54
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$57.54
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$56.23
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$74.13
Typical High
$112.20
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$87.10
Typical High
$147.91
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$83.18
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$47.86
Median
$64.57
Typical High
$79.43
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$47.86
Typical High
$56.23
United
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$56.23
United
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$56.23
Typical High
$66.07

Where Pennsylvania sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 26th of 51

$56.23

NC $58.88NY $54.95

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.