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Asparaginase (Rylaze) Injection

New York rates for HCPCS J9021

Injection, asparaginase, recombinant, (Rylaze), 0.1 mg

Rates data updated July 2026.

How much does Rylaze cost?

$54.95per 0.1 mg

Typical negotiated rate. In New York, July 2026.

Insurers have agreed to pay about $54.95 for each 0.1 mg of this drug. The price depends on where it is billed: about $54.95 from a physician practice, and about $74.13 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 0.1 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$54.95
At a hospital outpatient department
$74.13

The same drug, in the same amount, costs 35% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$54.95$52.48 to $56.23
FacilityA hospital or hospital-owned outpatient department$74.13$56.23 to $105

How much rates vary

Facilitymedian $74 · 10th to 90th $56 to $123Professionalmedian $55 · 10th to 90th $51 to $62
$100$200$500$1K$2K$5K$10Kfacility $74professional $55

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$79.43
Typical High
$131.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$64.57
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$58.88
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$56.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$61.66
Median
$74.13
Typical High
$81.28
Cigna
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$60.26
Emblem Health
Setting
Facility
Modifier
Global
Typical Low
$53.70
Median
$69.18
Typical High
$190.55
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$58.88
Excellus BCBS
Setting
Facility
Modifier
Global
Typical Low
$54.95
Median
$54.95
Typical High
$56.23
Excellus BCBS
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$56.23
Typical High
$56.23
MVP Health Care
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$50,118.72
Typical High
$75,857.76
MVP Health Care
Setting
Professional
Modifier
Global
Typical Low
$53.70
Median
$60.26
Typical High
$67.61
United
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$93.33
United
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$53.70
Typical High
$63.10
Univera
Setting
Facility
Modifier
Global
Typical Low
$54.95
Median
$54.95
Typical High
$64.57
Univera
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$56.23
Typical High
$56.23

Where New York sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New York· 51st of 51

$54.95

NC $58.88NY $54.95

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.