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Asparaginase (Rylaze) Injection

Nebraska rates for HCPCS J9021

Injection, asparaginase, recombinant, (Rylaze), 0.1 mg

Rates data updated October 2026.

How much does Rylaze cost?

$66.07per 0.1 mg

Typical negotiated rate. In Nebraska, October 2026.

Insurers have agreed to pay about $66.07 for each 0.1 mg of this drug. The price depends on where it is billed: about $66.07 from a physician practice, and about $58.88 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 0.1 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$66.07
At a hospital outpatient department
$58.88

The same drug, in the same amount, costs 11% less at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$66.07$56.23 to $83.18
FacilityA hospital or hospital-owned outpatient department$58.88$54.95 to $63.10

How much rates vary

Facilitymedian $59 · 10th to 90th $48 to $63Professionalmedian $66 · 10th to 90th $55 to $91
$50$100$200facility $59professional $66

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$56.23
Median
$56.23
Typical High
$58.88
Aetna
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$58.88
Typical High
$58.88
BCBS Nebraska
Setting
Facility
Modifier
None
Typical Low
$47.86
Median
$61.66
Typical High
$63.10
BCBS Nebraska
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$69.18
Typical High
$69.18
Cigna
Setting
Professional
Modifier
None
Typical Low
$67.61
Median
$83.18
Typical High
$87.10
Medica
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$104.71
Typical High
$269.15
Medica
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$63.10
Typical High
$239.88
Midlands
Setting
Professional
Modifier
None
Typical Low
$83.18
Median
$87.10
Typical High
$91.20
Midlands
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$91.20
Typical High
$138.04
United
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
United
Setting
Professional
Modifier
None
Typical Low
$53.70
Median
$56.23
Typical High
$67.61

Where Nebraska sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 3rd of 51

$66.07

AK $72.44LA $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.