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Asparaginase (Rylaze) Injection

Missouri rates for HCPCS J9021

Injection, asparaginase, recombinant, (Rylaze), 0.1 mg

Rates data updated October 2026.

How much does Rylaze cost?

$60.26per 0.1 mg

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $60.26 for each 0.1 mg of this drug. The price depends on where it is billed: about $60.26 from a physician practice, and about $79.43 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 0.1 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$60.26
At a hospital outpatient department
$79.43

The same drug, in the same amount, costs 32% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$60.26$58.88 to $67.61
FacilityA hospital or hospital-owned outpatient department$79.43$60.26 to $148

How much rates vary

Facilitymedian $79 · 10th to 90th $56 to $195Professionalmedian $60 · 10th to 90th $56 to $240
$50$100$200facility $79professional $60

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$56.23
Median
$60.26
Typical High
$93.33
Aetna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$60.26
Typical High
$70.79
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$79.43
Typical High
$194.98
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$57.54
Median
$67.61
Typical High
$67.61
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$64.57
Median
$64.57
Typical High
$117.49
Cigna
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$128.82
Typical High
$151.36
Cigna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
Medica
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$61.66
Typical High
$269.15
Medica
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$239.88
Typical High
$239.88
United
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
United
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$58.88
Typical High
$66.07

Where Missouri sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 15th of 51

$60.26

AK $72.44LA $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.