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Asparaginase (Rylaze) Injection

Michigan rates for HCPCS J9021

Injection, asparaginase, recombinant, (Rylaze), 0.1 mg

Rates data updated October 2026.

How much does Rylaze cost?

$60.26per 0.1 mg

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $60.26 for each 0.1 mg of this drug. The price depends on where it is billed: about $60.26 from a physician practice, and about $129 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 0.1 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$60.26
At a hospital outpatient department
$129

The same drug, in the same amount, costs 114% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$60.26$58.88 to $63.10
FacilityA hospital or hospital-owned outpatient department$129$70.79 to $174

How much rates vary

Facilitymedian $129 · 10th to 90th $60 to $209Professionalmedian $60 · 10th to 90th $58 to $76
$100$200$500facility $129professional $60

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$60.26
Median
$162.18
Typical High
$181.97
Aetna
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$60.26
Typical High
$60.26
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$64.57
Median
$125.89
Typical High
$239.88
BCBS Michigan
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$60.26
Typical High
$60.26
BCBS Michigan
Setting
Professional
Modifier
JW · Drug discarded
Typical Low
$53.70
Median
$56.23
Typical High
$56.23
Cigna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$60.26
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$158.49
Typical High
$181.97
Health Alliance Plan
Setting
Professional
Modifier
None
Typical Low
$57.54
Median
$58.88
Typical High
$77.62
Priority Health
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$60.26
United
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
United
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$63.10
Typical High
$66.07

Where Michigan sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 11th of 51

$60.26

AK $72.44LA $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.