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Asparaginase (Rylaze) Injection

Illinois rates for HCPCS J9021

Injection, asparaginase, recombinant, (Rylaze), 0.1 mg

Rates data updated October 2026.

How much does Rylaze cost?

$58.88per 0.1 mg

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $58.88 for each 0.1 mg of this drug. The price depends on where it is billed: about $58.88 from a physician practice, and about $120 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 0.1 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$58.88
At a hospital outpatient department
$120

The same drug, in the same amount, costs 104% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$58.88$58.88 to $61.66
FacilityA hospital or hospital-owned outpatient department$120$81.28 to $182

How much rates vary

Facilitymedian $120 · 10th to 90th $59 to $282Professionalmedian $59 · 10th to 90th $56 to $65
$100$200$500facility $120professional $59

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$77.62
Typical High
$208.93
Aetna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$204.17
Typical High
$457.09
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$69.18
Typical High
$69.18
Cigna
Setting
Facility
Modifier
None
Typical Low
$81.28
Median
$117.49
Typical High
$147.91
Cigna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$60.26
Hally Health
Setting
Professional
Modifier
None
Typical Low
$53.70
Median
$70.79
Typical High
$125.89
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$72.44
Median
$72.44
Typical High
$72.44
Molina
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$70.79
Typical High
$83.18
United
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$131.83
United
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$61.66
Typical High
$64.57

Where Illinois sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 36th of 51

$58.88

AK $72.44LA $58.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.