How much does Methotrexate, Oral cost?

$0.15per 2.5 mg

Typical negotiated rate. In Rhode Island, July 2026.

Insurers have agreed to pay about $0.15 for each 2.5 mg of this drug. The price depends on where it is billed: about $0.15 from a physician practice, and about $0.16 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 2.5 mg. Enter the amount given to see what insurers have agreed to pay for it.

Amount givenmg

In a doctor's office or clinic: $0.15
At a hospital outpatient department: $0.16

The same drug, in the same amount, costs 5% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed by	Who charges it	Typical	Range
Physician practiceA doctor's office, clinic or independent provider	A doctor's office, clinic or independent provider	$0.15	$0.14 to $0.15
FacilityA hospital or hospital-owned outpatient department	A hospital or hospital-owned outpatient department	$0.16	$0.15 to $0.28

How much rates vary

Facilitymedian $0 · 10th to 90th $0 to $0Professionalmedian $0 · 10th to 90th $0 to $0

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Aetna Setting Facility Modifier Global Typical Low $0.28 Median $0.46 Typical High $0.46	Facility	Global	$0.28	$0.46	$0.46
Aetna Setting Professional Modifier Global Typical Low $0.14 Median $0.15 Typical High $0.15	Professional	Global	$0.14	$0.15	$0.15
BCBS Setting Facility Modifier Global Typical Low $0.15 Median $0.15 Typical High $0.16	Facility	Global	$0.15	$0.15	$0.16
BCBS Setting Professional Modifier Global Typical Low $0.15 Median $0.15 Typical High $0.15	Professional	Global	$0.15	$0.15	$0.15
Cigna Setting Facility Modifier Global Typical Low $0.14 Median $0.15 Typical High $0.28	Facility	Global	$0.14	$0.15	$0.28
Cigna Setting Professional Modifier Global Typical Low $0.14 Median $0.14 Typical High $0.14	Professional	Global	$0.14	$0.14	$0.14
United Setting Professional Modifier Global Typical Low $0.14 Median $0.15 Typical High $0.17	Professional	Global	$0.14	$0.15	$0.17

Where Rhode Island sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Rhode Island· 11th of 51

$0.15

IA $0.17DE $0.14

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.