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Factor IX Fc Fusion Protein (Alprolix) Injection

Minnesota rates for HCPCS J7201

Injection, Factor IX, Fc fusion protein, (recombinant), Alprolix, 1 IU

Rates data updated October 2026.

How much does Alprolix cost?

$3.72per IU

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $3.72 for each IU of this drug. The price depends on where it is billed: about $3.63 from a physician practice, and about $5.01 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per IU. Enter the amount given to see what insurers have agreed to pay for it.

IU
In a doctor's office or clinic
$3.63
At a hospital outpatient department
$5.01

The same drug, in the same amount, costs 38% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3.63$3.55 to $3.80
FacilityA hospital or hospital-owned outpatient department$5.01$3.72 to $7.24

How much rates vary

Facilitymedian $5 · 10th to 90th $4 to $10Professionalmedian $4 · 10th to 90th $3 to $5
$5$10facility $5professional $4

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$3.72
Median
$3.72
Typical High
$3.72
Aetna
Setting
Professional
Modifier
None
Typical Low
$3.72
Median
$3.72
Typical High
$3.80
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$3.63
Median
$5.37
Typical High
$7.24
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$2.88
Median
$3.24
Typical High
$3.55
Cigna
Setting
Facility
Modifier
None
Typical Low
$4.79
Median
$9.77
Typical High
$13.18
Cigna
Setting
Professional
Modifier
None
Typical Low
$3.80
Median
$4.17
Typical High
$4.79
Health Partners
Setting
Facility
Modifier
None
Typical Low
$3.72
Median
$9.12
Typical High
$13.80
Health Partners
Setting
Professional
Modifier
None
Typical Low
$3.80
Median
$3.80
Typical High
$3.80
Medica
Setting
Facility
Modifier
None
Typical Low
$3.63
Median
$4.37
Typical High
$6.76
Medica
Setting
Professional
Modifier
None
Typical Low
$3.63
Median
$3.63
Typical High
$6.61
United
Setting
Facility
Modifier
None
Typical Low
$3.72
Median
$3.72
Typical High
$3.72
United
Setting
Professional
Modifier
None
Typical Low
$3.55
Median
$3.55
Typical High
$6.61
8 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$1.86
Median
$1.86
Typical High
$1.86
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$0.74
Median
$0.74
Typical High
$0.74
Aetna
Setting
Facility
Modifier
55 · Aftercare only
Typical Low
$0.56
Median
$0.56
Typical High
$0.56
Aetna
Setting
Facility
Modifier
56 · Pre-op care only
Typical Low
$0.37
Median
$0.37
Typical High
$0.37
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1.86
Median
$1.86
Typical High
$1.91
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$0.74
Median
$0.74
Typical High
$0.76
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$0.56
Median
$0.56
Typical High
$0.56
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$0.37
Median
$0.37
Typical High
$0.38

Where Minnesota sits

The same service costs 1.9 times more in Alaska than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 33rd of 51

$3.72

AK $6.61RI $3.55

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.