How much does Amphadase (hyaluronidase) cost?

$69.18per 150 units

Typical negotiated rate. In West Virginia, July 2026.

Insurers have agreed to pay about $69.18 for each 150 units of this drug. The price depends on where it is billed: about $31.62 from a physician practice, and about $132 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 150 units. Enter the amount given to see what insurers have agreed to pay for it.

Amount givenunits

In a doctor's office or clinic: $31.62
At a hospital outpatient department: $132

The same drug, in the same amount, costs 317% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 3 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed by	Who charges it	Typical	Range
Physician practiceA doctor's office, clinic or independent provider	A doctor's office, clinic or independent provider	$31.62	$31.62 to $69.18
FacilityA hospital or hospital-owned outpatient department	A hospital or hospital-owned outpatient department	$132	$129 to $132

How much rates vary

Facilitymedian $132 · 10th to 90th $32 to $132Professionalmedian $32 · 10th to 90th $32 to $69

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Aetna Setting Facility Modifier Global Typical Low $31.62 Median $131.83 Typical High $131.83	Facility	Global	$31.62	$131.83	$131.83
Aetna Setting Professional Modifier Global Typical Low $31.62 Median $31.62 Typical High $69.18	Professional	Global	$31.62	$31.62	$69.18
Cigna Setting Facility Modifier Global Typical Low $31.62 Median $46.77 Typical High $85.11	Facility	Global	$31.62	$46.77	$85.11
Cigna Setting Professional Modifier Global Typical Low $31.62 Median $31.62 Typical High $134.90	Professional	Global	$31.62	$31.62	$134.90
United Setting Facility Modifier Global Typical Low $52.48 Median $52.48 Typical High $52.48	Facility	Global	$52.48	$52.48	$52.48
United Setting Professional Modifier Global Typical Low $30.90 Median $31.62 Typical High $57.54	Professional	Global	$30.90	$31.62	$57.54

Where West Virginia sits

The same service costs 2.2 times more in West Virginia than in New Hampshire. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

West Virginia· 1st of 51

$69.18

WV $69.18NH $31.62

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.