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Hyaluronidase Injection, up to 150 units

North Carolina rates for HCPCS J3470 · Amphadase

Injection, hyaluronidase, up to 150 units

Rates data updated October 2026.

How much does Amphadase (hyaluronidase) cost?

$36.31per 150 units

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $36.31 for each 150 units of this drug. The price depends on where it is billed: about $31.62 from a physician practice, and about $51.29 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 150 units. Enter the amount given to see what insurers have agreed to pay for it.

units
In a doctor's office or clinic
$31.62
At a hospital outpatient department
$51.29

The same drug, in the same amount, costs 62% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$31.62$31.62 to $57.54
FacilityA hospital or hospital-owned outpatient department$51.29$35.48 to $57.54

How much rates vary

Facilitymedian $51 · 10th to 90th $35 to $71Professionalmedian $32 · 10th to 90th $32 to $59
$20$50facility $51professional $32

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$57.54
Typical High
$70.79
Aetna
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$57.54
Typical High
$57.54
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$16.60
Median
$28.18
Typical High
$28.18
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$6.61
Median
$11.48
Typical High
$11.48
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$4.90
Median
$8.51
Typical High
$8.51
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$3.31
Median
$5.75
Typical High
$5.75
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$56.23
Median
$56.23
Typical High
$67.61
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$31.62
Median
$58.88
Typical High
$58.88
Cigna
Setting
Facility
Modifier
None
Typical Low
$35.48
Median
$47.86
Typical High
$67.61
Cigna
Setting
Professional
Modifier
None
Typical Low
$31.62
Median
$31.62
Typical High
$67.61
Medcost
Setting
Facility
Modifier
None
Typical Low
$38.02
Median
$38.02
Typical High
$57.54
Medcost
Setting
Professional
Modifier
None
Typical Low
$14.79
Median
$14.79
Typical High
$14.79
United
Setting
Professional
Modifier
None
Typical Low
$31.62
Median
$31.62
Typical High
$48.98

Where North Carolina sits

The same service costs 3.8 times more in Alabama than in Virginia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 13th of 51

$36.31

AL $120VA $31.62

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.