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Hyaluronidase Injection, up to 150 units

Missouri rates for HCPCS J3470 · Amphadase

Injection, hyaluronidase, up to 150 units

Rates data updated October 2026.

How much does Amphadase (hyaluronidase) cost?

$31.62per 150 units

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $31.62 for each 150 units of this drug. The price depends on where it is billed: about $31.62 from a physician practice, and about $54.95 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 150 units. Enter the amount given to see what insurers have agreed to pay for it.

units
In a doctor's office or clinic
$31.62
At a hospital outpatient department
$54.95

The same drug, in the same amount, costs 74% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$31.62$31.62 to $38.02
FacilityA hospital or hospital-owned outpatient department$54.95$42.66 to $75.86

How much rates vary

Facilitymedian $55 · 10th to 90th $32 to $95Professionalmedian $32 · 10th to 90th $32 to $68
$20$50$100$200facility $55professional $32

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$31.62
Median
$67.61
Typical High
$93.33
Aetna
Setting
Professional
Modifier
None
Typical Low
$31.62
Median
$31.62
Typical High
$67.61
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$31.62
Median
$42.66
Typical High
$83.18
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$31.62
Median
$34.67
Typical High
$67.61
Cigna
Setting
Facility
Modifier
None
Typical Low
$36.31
Median
$54.95
Typical High
$74.13
Cigna
Setting
Professional
Modifier
None
Typical Low
$31.62
Median
$31.62
Typical High
$31.62
Medica
Setting
Facility
Modifier
None
Typical Low
$21.38
Median
$75.86
Typical High
$251.19
Medica
Setting
Professional
Modifier
None
Typical Low
$28.84
Median
$31.62
Typical High
$36.31
United
Setting
Professional
Modifier
None
Typical Low
$31.62
Median
$31.62
Typical High
$38.90
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$15.85
Median
$15.85
Typical High
$33.11
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$6.31
Median
$6.31
Typical High
$13.49
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$4.79
Median
$4.79
Typical High
$10.00
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$3.16
Median
$3.16
Typical High
$6.76

Where Missouri sits

The same service costs 3.8 times more in Alabama than in Virginia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 39th of 51

$31.62

AL $120VA $31.62

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.