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Vestronidase Alfa-vjbk Injection

Pennsylvania rates for HCPCS J3397 · Mepsevii

Injection, vestronidase alfa-vjbk, 1 mg

Rates data updated July 2026.

How much does Mepsevii (vestronidase alfa) cost?

$288per mg

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $288 for each mg of this drug. The price depends on where it is billed: about $288 from a physician practice, and about $447 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$288
At a hospital outpatient department
$447

The same drug, in the same amount, costs 55% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$288$288 to $288
FacilityA hospital or hospital-owned outpatient department$447$288 to $741

How much rates vary

Facilitymedian $447 · 10th to 90th $288 to $851Professionalmedian $288 · 10th to 90th $288 to $288
$500$1K$2K$5Kfacility $447professional $288

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$446.68
Typical High
$851.14
Aetna
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$281.84
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$281.84
Typical High
$281.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$1,000.00
Typical High
$1,071.52
Cigna
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$436.52
Typical High
$812.83
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$741.31
United
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$281.84
United
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$389.05

Where Pennsylvania sits

The same service costs 1.7 times more in Colorado than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 15th of 51

$288

CO $468NC $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.